This work has provided a novel technique for preparation, characterization, and utilization of mesoporous silica SBA-15 in waste treatment to remove methylene blue as an organic pollutant and copper(II) as inorganic pollutant sampling with a photocatalytic adsorption system. To process of mesoporous silica SBA-15 was prepared by the sol-gel method for Pluronic as a surfactant template and following the hydrothermal process to high interaction between Pluronik and tetraethyl ortho silicate (TEOS) as precursor reagent. The proceed materials were characterized by the surface analyzer, X-ray diffraction, and Fourier transform infrared. Mesoporous silica SBA-15 was obtained with hexagonal structure having 72 percent amorphous content, high surface area, large pore-volume, approximately 948 m2/g, and 1.3 cm3/g. The second major finding was that mesoporous silica SBA-15 have a high photocatalytic adsorption capacity to remove methylene blue and copper(II). These present results suggest several courses of action in order to utilize SBA-15 samples in waste treatment